What is PEP?

PEP, or post-exposure prophylaxis, is a combination of medications that an HIV-negative person takes for 28-30 days AFTER a possible exposure to HIV. PEP is most effective the sooner it’s started, and must be started within 72 hours of the exposure.

Common PEP Questions

How do I know if I need PEP?

Within the past 72 hours, have you been exposed to the pre-cum, cum, vaginal fluid, rectal fluid or blood of someone who is:

  1. living with HIV and you do not know if they have an undetectable viral load or
  2. do not know their HIV status? If so, you may benefit from PEP.

How do I know if I need PEP?

A clinician must prescribe PEP. During regular office hours, ask your doctor or go to a sexual health clinic. During off hours, go to an urgent care or emergency room. For more information, check out our downloadable PEP info sheet from PleasePrEPMe.org.